Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves
AA Khalil, S Steyn, N Castagnoli
Index: Khalil, Ashraf A.; Steyn, Salome; Castagnoli Jr., Neal Chemical Research in Toxicology, 2000 , vol. 13, # 1 p. 31 - 35
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Citation Number: 92
Abstract
Recent positron emission tomography imaging studies have demonstrated a significant decrease in both monoamine oxidase A and B (MAO-A and MAO-B) activities in the brains of smokers. Normal levels of activity are observed in former smokers, suggesting the presence of one or more compounds in tobacco smoke that may inhibit these enzymes. In this paper, we report the results of efforts to identify compounds present in flue-cured tobacco leaves ...
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