NHC-initiated cascade, metal-free synthesis of quinoxaline derivatives under solvent-free conditions
L Gao, R Liu, C Yu, C Yao, T Li, Z Xiao
Index: Gao, Lijiu; Liu, Rui; Yu, Chenxia; Yao, Changsheng; Li, Tuanjie; Xiao, Zhaoxin Research on Chemical Intermediates, 2014 , vol. 40, # 5 p. 2131 - 2138
Full Text: HTML
Citation Number: 2
Abstract
Abstract 2, 3-Diaryl quinoxaline derivatives have been efficiently synthesized by cascade, metal-free, and solvent-free reaction of aryl aldehydes with aryl 1, 2-diamines initiated by N- heterocyclic carbene. Compared with reported methods, this procedure has the advantages of easy work-up, reduced energy consumption, and elimination of solvent waste, hazards, and toxicity. A group of potentially bioactive compounds has been prepared for biomedical ...
Related Articles:
[Ochoa, Carmen; Rodriguez, Juan Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 1053 - 1055]
N-Heterocyclic carbene catalyzed one-pot synthesis of 2, 3-diarylquinoxalines
[Lin, Yang; Lei, Xiaoli; Yang, Qin; Yuan, Jiangjun; Ding, Qiuping; Xu, Jingshi; Peng, Yiyuan Synthesis (Germany), 2012 , vol. 44, # 17 p. 2699 - 2706]