Canadian Journal of Chemistry

The conversion of α-keto acids and of α-keto acid oximes to nitriles in aqueous solution

A Ahmad, ID Spenser

Index: Ahmad,A.; Spenser,I.D. Canadian Journal of Chemistry, 1961 , vol. 39, p. 1340 - 1359

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Citation Number: 55

Abstract

The conversion of α-oximino acids (anti HO--COOH) to nitriles in aqueous solution is shown to be a general reaction. α-Keto acids are converted to nitriles in excellent yield in aqueous solution in the presence of hydroxylamine. Oxidation of α-oximino acids yields hydroxamic acids.