Synlett

Ceric ammonium nitrate (CAN) promoted efficient synthesis of 1, 5-benzodiazepine derivatives

R Varala, R Enugala, S Nuvula, SR Adapa

Index: Varala, Ravi; Enugala, Ramu; Nuvula, Sreelatha; Adapa, Srinivas R. Synlett, 2006 , # 7 p. 1009 - 1014

Full Text: HTML

Citation Number: 90

Abstract

Abstract Ceric ammonium nitrate was found to be an efficient reagent for the preparation of 1, 5-benzodiazepine derivatives of a wide range of substituted o-phenylenediamines and electronically divergent ketones in moderate to excellent isolated yields (60-98%) under mild conditions using methanol as solvent at ambient temperature.