Tetrahedron

Derivatives and reactions of glutacondialdehyde IV 1-substituted-3-formyl-2 (1H)-pyridinethiones

J Becher, EG Frandsen

Index: Becher,J.; Frandsen,E.G. Tetrahedron, 1977 , vol. 33, p. 341 - 343

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Citation Number: 20

Abstract

The reaction of the glutacondialdehyde anion with alkyl and acyl isothiocyanates has been investigated. Whereas alkyl isothiocyanates give rise to 1-alkyl-3-formyl-2 (1H)- pyridinethiones, O-acylated glutacondialdehyde derivatives are formed from acyl isothiocyanates in most cases. The reaction courses may be understood on the basis of the principle of hard and soft acids and bases.