Tetrahedron letters

Benzo [b] thiophene as a template for substituted quinolines and tetrahydroquinolines

JFD Chabert, G Chatelain, S Pellet-Rostaing…

Index: Fournier Dit Chabert, Jeremie; Chatelain, Gregory; Pellet-Rostaing, Stephane; Bouchu, Denis; Lemaire, Marc Tetrahedron Letters, 2006 , vol. 47, # 6 p. 1015 - 1018

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Citation Number: 27

Abstract

An original methodology starting from 3-aroyl-2-(2′-nitro-4′-methoxyphenyl)-benzo [b] thiophene allows the synthesis of unusual fused heterocycles. Direct hydrogenation with nickel catalysts followed by desulfurisation led to 2, 3-diarylquinolines or 2, 3- diaryltetrahydroquinolines.