Synlett

Copper (II) Acetate Catalyzed Cross-Coupling of Pentafluorophenylboronic Acid with Amines under an Atmosphere of Oxygen

W Zhong, Z Liu, C Yu, W Su

Index: Zhong, Weihui; Liu, Zhenyu; Yu, Chuanming; Su, Weike Synlett, 2008 , # 18 p. 2888 - 2892

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Citation Number: 9

Abstract

Abstract Under an atmosphere of oxygen and a catalytic amount of Cu (OAc) 2, pentafluorophenylboronic acid reacted with anilines at room temperature to produce the corresponding N-pentafluorophenylanilines in moderate to good yields. In the case of alkylamines, unexpected N-alkyl-2, 2′, 3, 3′, 4′, 5, 5′, 6, 6′-nona-fluoro-biphenyl-4- amines were formed under the similar conditions in moderate yields.

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