A convenient synthesis of highly substituted furans by microwave irradiation of ring-fused alkylidenecyclopropanes
MA Chowdhury, H Senboku, M Tokuda
Index: Chowdhury, Morshed Alam; Senboku, Hisanori; Tokuda, Masao Synlett, 2004 , # 11 p. 1933 - 1936
Full Text: HTML
Citation Number: 0
Abstract
Methyl- and phenyl ketones 1a and 1b under microwave irradiation at 200 °C for five minutes afforded 2-methyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]furan (2a) and 2-phenyl-5,6,7,8-tetrahydro -4H-cyclohepta[b]furan (2b) in 78% and 61% isolated yields, respectively (entries 1 and 2). Similarly, 1c and 1d afforded 2,3-dimethyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]furan (2c) and 3-methyl-2-phenyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]furan (2d) in 63% and 80% ...
Related Articles:
Readily Prepared 3-Chloro-1-(phenylthio) propene, a Versatile Three-Carbon Annulating Agent
[Chen, Wenbo; Zhao, Xiaoming; Lu, Long; Cohen, Theodore Organic Letters, 2006 , vol. 8, # 10 p. 2087 - 2090]
[Hosomi, Akira; Shirahata, Akihiko; Araki, Yoshitaka; Sakurai, Hideki Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4631 - 4633]