Iodine catalysed synthesis and antibacterial evaluation of thieno [2, 3-d] pyrimidine derivatives

…, G Bagherzadeh, M Vaseghifar, A Shiri…

Index: Bakavoli, Mehdi; Bagherzadeh, Ghodsieh; Vaseghifar, Maryam; Shiri, Ali; Pordeli, Parvaneh Journal of Chemical Research, 2009 , # 11 p. 653 - 655

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Citation Number: 10

Abstract

Abstract A new route via iodine catalysed heterocyclisation of 2-amino-4, 5- dimethylthiophene-3-carboxamide with aromatic aldehydes affording a series of thieno [2, 3- d] pyrimidine derivatives in a single step have been developed. Some of these compounds exhibited antibacterial activities comparable to Streptomycin as reference drug.