Chemistry letters

Synthesis of 5-(alkylphenylphosphoryl)-5-methyl-3, 4-dihydro-2H-pyrroline N-oxide as a new spin trapping reagent

K Shioji, S Tsukimoto, H Tanaka, K Okuma

Index: Shioji, Kosei; Tsukimoto, Shigeyuki; Tanaka, Hidehiko; Okuma, Kentaro Chemistry Letters, 2003 , vol. 32, # 7 p. 604 - 605

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Citation Number: 12

Abstract

Novel DMPO analogues attached to a phenyl group at the phosphorus atom were synthesized and examined for their abil- ity in the spin trapping of oxygen-centered radicals. The lipo- philicities of these analogues were higher than those of DMPO. ... Spin trapping studies have been applied to the detection of oxygen-centered radicals in biological processes.1 ... Table 1. These signals were inhibited by the presence of cata- lase (50 U/mL). ... The trapping of superoxide ...