Tetrahedron letters

Enantioselective synthesis of C 2-symmetric diols

GJ Quallich, KN Keavey, TM Woodall

Index: Quallich, George J.; Keavey, Kenneth N.; Woodall, Teresa M. Tetrahedron Letters, 1995 , vol. 36, # 27 p. 4729 - 4732

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Citation Number: 51

Abstract

Catalytic reduction of diketones with erythro diphenyl oxazaborolidine yielded C2-symmetric diols in high enantiomeric excess. Enantiomeric excess increased and less meso isomer was generated when borane was employed equimolar with respect to the carbonyl groups and when stoichiometric oxazaborolidine was used.