Tetrahedron Letters

Cesium hydroxide-promoted aerobic oxidation of sec-aromatic alcohols

W Zhang, M Liu, H Wu, J Ding, J Cheng

Index: Zhang, Weiwei; Liu, Miaochang; Wu, Huayue; Ding, Jinchang; Cheng, Jiang Tetrahedron Letters, 2008 , vol. 49, # 36 p. 5336 - 5338

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Citation Number: 20

Abstract

In our previous work, we found that the combination of K 2 CO 3 , PdCl 2 and P(1-nap) 3 in THF could efficiently catalyze the reaction of aryl aldehydes with aryl boronic acids, providing the carbinol derivatives in good yield. During the researching process, we found that aryl ketones were formed. Interestingly, the employment of Cs 2 CO 3 instead of K 2 CO 3 provides the aryl ketones in moderate to good yields under air (Eq. 1). 8 The desired products were at least ...