Regioselective Synthesis of (E)-5-(Tributylstannylmethylidene)-5H-furan-2-ones and (E)-3-(Tributylstannylmethylidene)-3H-isobenzofuran-1-ones: Easy Access to γ- …

A Duchene, J Thibonnet, JL Parrain, E Anselmi…

Index: Duchene, Alain; Thibonnet, Jerome; Parrain, Jean-Luc; Anselmi, Elsa; Abarbri, Mohamed Synthesis, 2007 , # 4 p. 597 - 607

Full Text: HTML

Citation Number: 15

Abstract

Abstract Regio-and stereoselective synthesis of γ-alkylidenebutenolides and γ- alkylidenephthalides has been achieved through the palladium-catalysed tandem cross- coupling/cyclisation reactions of tributylstannyl-3-iodopropenoate or the 2-iodo benzoate derivatives with tributyltinacetylene. Iododestannylation occurred with inversion of the configuration of the exocyclic double bond in the case of butenolides, but with retention of ...