Journal of Fluorine Chemistry

Synthesis of perfluoroaliphatic Grignard reagents

DD Denson, CF Smith, C Tamborski

Index: Denson, D. D.; Smith, C. F.; Tamborski, C. Journal of Fluorine Chemistry, 1973 , vol. 3, p. 247 - 258

Full Text: HTML

Citation Number: 28

Abstract

Abstract Perfluoraliphatic mono-and di-Grignard reagents (R f MgX, XMgR′ f MgX) have been conveniently synthesized in excellent yields (90–100%) through metalhalogen exchange reactions. The degree of exchange has been found to be subject to a number of experimental parameters, eg the nature of the solvent (tetrahydrofuran vis-à-vis diethyl ether), the type of halide displaced, the organomagnesium exchange reagent and the ...