Enzymic resolution of cyclopropanols. An easy access to optically active cyclohexanones possessing an. alpha.-quaternary chiral carbon

…, L Blanco, G Rousseau, E Guibe-Jampel…

Index: Barnier, Jean-Pierre; Blanco, Luis; Rousseau, Gerard; Guibe-Jampel, Eryka; Fresse, Isabelle Journal of Organic Chemistry, 1993 , vol. 58, # 6 p. 1570 - 1574

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Citation Number: 28

Abstract

The chemistry of cyclopropanols has been thoroughly studied,'and useful applications of their cleavage by electrophiles have been However optically active cyclopropanols and derivatives are rare. 3 They have been generally obtained by chemical transformation of optically active compounds? Recently, Reissig reported the enantioselective preparation of (si1oxy) cyclopropanes (ee< 37%) by a copper-catalyzed cyclopropanation of silyl enol ...