Difluorophenylsulfanylmethyl Radical and Difluoromethylene Diradical Synthons: g em-Difluoromethylene Building Block

…, P Tuchinda, C Kuhakarn, M Pohmakotr

Index: Reutrakul, Vichai; Thongpaisanwong, Thanchanok; Tuchinda, Patoomratana; Kuhakarn, Chutima; Pohmakotr, Manat Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6913 - 6915

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Citation Number: 45

Abstract

Bromodifluorophenylsulfanylmethane has been demonstrated to be a highly versatile gem- difluoromethylene (CF2) building block via the reaction of difluorophenylsulfanylmethyl radical with olefins. gem-Difluoroalkenes and products containing a midchain CF2 group and with manipulatable functionality can be readily synthesized. The first example of a gem- difluoromethylene radical synthon is also reported.