Synthetic hosts for molecular recognition of ureas

…, MR Torres, J Elguero, RM Claramunt

Index: Maria, Dolores Santa; Farran, M. Angeles; Garcia, M. Angeles; Pinilla, Elena; Torres, M. Rosario; Elguero, Jose; Claramunt, Rosa M. Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6780 - 6788

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Citation Number: 7

Abstract

Four hosts (7–10) containing 2, 6-bisamidopyridine-and 2, 5-bisamidopyrrole-bearing pyridyl or 1, 8-naphthyridyl groups have been prepared and their structures studied by a combination of multinuclear NMR spectroscopy and X-ray crystallography. Their behavior in molecular recognition of urea derivatives, including (+)-biotin methyl ester, has been approached by molecular modeling (Monte Carlo conformational search, AMBER force ...