Towards Allopumiliotoxins: A Concise Synthesis of the Indolizidine Core

…, P Mallesham, S Chandrasekhar

Index: Vijaykumar, Bodduri V. D.; Mallesham, Pitchakuntla; Chandrasekhar, Srivari European Journal of Organic Chemistry, 2012 , # 5 p. 988 - 994

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Citation Number: 2

Abstract

Abstract The common bicyclic indolizidine core present in several allopumiliotoxins was synthesized by the sequential use of a Crimmins' aldol reaction, an SOCl 2-mediated SN i displacement, and an intramolecular nucleophilic acyl substitution (INAS) as the key transformations.