Formation of 4-Hydroxy-3, 7-dimethyl-2, 6-octadienal (5-Hydroxycitral) from 3, 7-Dimethyl-2, 6-octadienal (Citral) and its Biological Activity against Sarcoma 180

R Iriye, T Yorifuji, N Takeda…

Index: Iriye; Yorifuji; Takeda; et al. Agricultural and Biological Chemistry, 1984 , vol. 48, # 12 p. 2923 - 2925

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Citation Number: 10

Abstract

4-Hydroxy-3, 7-dimethyl-2, 6-octadienal (5-Hydroxycitral)(2) was prepared from 3, 7- dimethyl-2, 6-octatrienal (citral)(1) via bromoaldehyde (4) and acetoxyaldehyde (6). 3, 7- Dimethyl-2, 4, 6-octadienal (7) was also obtained as a byproduct. 4-Hydroxy-3, 7-dimethyl-2, 6-octadienal (2) showed similar growth inhibition activity to that of 1 against Sarcoma 180.