A Synthetic Cycle for the Ruthenium-Promoted Formation of 1 H-Phosphindoles from Phosphaalkynes

JG Cordaro, D Stein, H Grützmacher

Index: Cordaro, Joseph G.; Stein, Daniel; Gruetzmacher, Hansjoerg Journal of the American Chemical Society, 2006 , vol. 128, # 46 p. 14962 - 14971

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Citation Number: 31

Abstract

Beginning with inexpensive and commercially available starting materials, a rational synthesis for the new phosphaalkyne Ph3C-C⋮ P (1) is presented. Coordination of 1 to group 8 transition metal centers furnishes the η1-complexes [MH (dppe) 2 (Ph3CC⋮ P)] OTf, where M= Fe (3) or Ru (4)(dppe= bis-1, 2-diphenylphosphinoethane). Treatment of 3 or 4 with a strong acid cyclizes the coordinated phosphaalkyne and is the first example of an ...