Genotoxic activity of halogenated phenylglycine derivatives

…, M Menacho-Márquez, A Orjales, CJ Saavedra

Index: Boto, Alicia; Gallardo, Juan A.; Hernandez, Rosendo; Ledo, Francisco; Munoz, Ana; Murguia, Jose R.; Menacho-Marquez, Mauricio; Orjales, Aurelio; Saavedra, Carlos J. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6073 - 6077

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Citation Number: 7

Abstract

The discovery of genotoxic amino acids derived from phenylglycine, and posessing halogen substituents, is described. The utility of hypervalent iodine reagents in the synthesis of this class of compounds is highlighted. The mechanism of action of the (haloaryl) glycines was ...