Copper-mediated hydroxylation of an arene: model system for the action of copper monooxygenases. Structures of a binuclear copper (I) complex and its oxygenated …

…, Y Gultneh, RW Cruse, JW McKown…

Index: Karlin, Kenneth D.; Hayes, Jon C.; Gultneh, Yilma; Cruse, Richard W.; McKown, Jeffrey W.; et al. Journal of the American Chemical Society, 1984 , vol. 106, # 7 p. 2121 - 2128

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Citation Number: 332

Abstract

Abstract: A chemical system possessing features that mimic the structures and reactivity of the active sites of the copper oxygen carrier hemocyanin (Hc) and the monooxygenase tyrosinase (Tyr) is presented. When a dinuclear 3-coordinate Cu (1) complex, 11, of a binucleating ligand, I, where the two tridentate nitrogen donor groups are separated by a rn- xylyl bridge is reacted with dioxygen, the specific hydroxylation of the aromatic ring occurs ...