Synthesis of diethyl 2-(aryl) vinylphosphonate by the Heck reaction catalysed by supported palladium catalysts

J Tarabay, W Al-Maksoud, F Jaber, C Pinel…

Index: Tarabay, Jinane; Al-Maksoud, Walid; Jaber, Farouk; Pinel, Catherine; Prakash, Swamy; Djakovitch, Laurent Applied Catalysis A: General, 2010 , vol. 388, # 1-2 p. 124 - 133

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Citation Number: 22

Abstract

The synthesis of diethyl 2-(aryl) vinylphosphonate through direct Heck coupling reaction of the diethyl vinylphosphonate with aryl or heteroaryl halides catalysed by solid materials ([Pd (NH3) 4]/NaY, Pd/C, PdO/SiO2) is reported. After optimising the reaction conditions (1.3 mol%[Pd (NH3) 4]/NaY, DMF, K2CO3, 110–140° C), various aryl and heteroaryl halides were engaged in this reaction leading in all cases good to high yields. Interestingly, when ...