Design, synthesis and characterization of a novel fluorescent probe for nitric oxide based on difluoroboradiaza-s-indacene fluorophore

X Zhang, H Zhang

Index: Zhang, Xian; Zhang, Hua-Shan Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2005 , vol. 61, # 6 p. 1045 - 1049

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Citation Number: 40

Abstract

Nitric oxide (NO) is a gaseous, free radical, which plays a role as an intracellular second messenger and a diffusible intercellular messenger. To obtain evidence for NO function in vivo, 1, 3, 5, 7-tetramethyl-8-(4′-aminophenyl-N-(2′′-amino)-phenzyl)-difluoroboradiaza- s-indacene (TMAPABODIPY) was designed and synthesized as a fluorescent probe for nitric oxide, which features high photostability and no pH dependency over a wide pH range. ...