Tetrahedron Letters

A formal total synthesis of the telomerase inhibitor dictyodendrin B

S Hirao, Y Yoshinaga, M Iwao, F Ishibashi

Index: Hirao, Shotaro; Yoshinaga, Yuki; Iwao, Masatomo; Ishibashi, Fumito Tetrahedron Letters, 2010 , vol. 51, # 3 p. 533 - 536

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Citation Number: 21

Abstract

A formal synthesis of the telomerase inhibitory marine pyrrolocarbazole alkaloid dictyodendrin B is described. The key features are consecutive palladium-catalyzed cross- coupling reactions and intramolecular reductive coupling reaction to construct the pyrrolo [2, 3-c] carbazole framework.