Some reactions of 1-methyl-1, 2-dihydropyridines with organic azides. Synthesis and reactions of 1, 2, 5, 6-tetrahydropyridylidene-2-cyan (sulfon) amides and …

TA Ondrus, PR Pednekar…

Index: Ondrus, Theodore A.; Pednekar, Purushottam R.; Knaus, Edward E. Canadian Journal of Chemistry, 1985 , vol. 63, p. 2362 - 2368

Full Text: HTML

Citation Number: 11

Abstract

The regiospecific 1, 3-dipolar cycloaddition reaction of 1, 2-dihydropyridines 2 with organic azides 3 affords 2, 7-diazabicyclo [4.1. 0] hept-4-enes 4. Treatment of 4 a with neutral aluminum oxide opened the aziridine ring to afford the 1, 2, 5, 6-tetrahydropyridylidene-2- cyanamide 5. Catalytic hydrogenation of 4 and 5 using palladium-on-charcoal and hydrogen yielded the 1-methyl-2-piperidylidenes 6. Oxidation of 1-methyl-1, 2, 5, 6- ...