One-Pot Synthesis of γ, δ-Unsaturated Carbonyl Compounds from Allyl Alcohols and Vinyl or Isopropenyl Acetates Catalyzed by [IrCl (cod)] 2
M Morita, S Sakaguchi, Y Ishii
Index: Morita, Masao; Sakaguchi, Satoshi; Ishii, Yasutaka Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 6285 - 6286
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Citation Number: 9
Abstract
One-pot synthesis of γ, δ-unsaturated carbonyl compounds from allyl alcohols and vinyl or isopropenyl acetates was achieved through in situ generation of allyl vinyl ethers by the action of the [IrCl (cod)] 2 complex followed by Claisen rearrangement of the resulting ethers. For instance, the reaction of trans-2-methyl-3-phenyl-2-propen-1-ol with isopropenyl acetate in the presence of [IrCl (cod)] 2 (1 mol%) and Cs2CO3 (5 mol%) at 100° C for 3 h ...
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