Tetrahedron Letters

A short and efficient synthesis of renealtins A and B

G Sabitha, K Yadagiri, JS Yadav

Index: Sabitha, Gowravaram; Yadagiri; Yadav Tetrahedron Letters, 2007 , vol. 48, # 45 p. 8065 - 8068

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Citation Number: 19

Abstract

The total syntheses of the first examples of diarylheptanoid natural products, renealtins A (1) and B (2), isolated from Renealmia exaltata are described, utilizing a δ-lactone intermediate 9. The key reactions involved are asymmetric dihydroxylation and oxy-Michael addition.

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