Study of the syntheses and properties of 5, 12-diaza [24](1, 2, 4, 5) cyclophane and 5, 15-diaza [24](1, 2, 4, 5) cyclophane

HC Kang, V Boekelheide

Index: Kang,H.C.; Boekelheide,V. Journal of the American Chemical Society, 1984 , vol. 106, p. 2672

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Citation Number: 8

Abstract

Abstract: The conversion of diethyl 2, 6-dimethylpyridine-3, 5-dicarboxylate (5) to 5, 12-diaza [2,](1, 2, 4, 5) cyclophane (2) and to 5, 15-diaza [24](1, 2, 4, 5) cyclophane (3) has been accomplished in seven steps using the o-xylylene dimerization procedure involving 3- carbomethoxy-2-methyl [5, 6] cyclobutapyridine (8), 7, 13-bis (chloromethyl)-6, 14-dimethyl- 5, 15-dia~ a [2~](1, 2) cyclophane (13), and 7, 14-bis (chloromethyl)-6, 13-dimethyl-5, 12- ...