2, 4??and 2, 5??Disubstituted Arylthiazoles: Rapid Synthesis by C–H Coupling and Biological Evaluation
…, TN Uehara, S Tani, J Yamaguchi…
Index: Lohrey, Lilia; Uehara, Takahiro N.; Tani, Satoshi; Yamaguchi, Junichiro; Humpf, Hans-Ulrich; Itami, Kenichiro European Journal of Organic Chemistry, 2014 , vol. 2014, # 16 p. 3387 - 3394
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Abstract
Abstract Life-threatening infections caused by bacteria that have developed resistance to common antibiotics, such as methicillin-resistant Staphylococcus aureus (MRSA), have become a serious problem in hospitals and other areas all over the world. Thus, the development of an effective class of antibiotics against these bacteria is an urgent subject. Herein, we report a step-economical and diversity-oriented synthesis of a series of 2- ...
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