An Efficient Synthesis of gem??Dihydroperoxides with Molecular Oxygen and Anthracene under Light Irradiation

N Tada, L Cui, H Okubo, T Miura…

Index: Tada, Norihiro; Cui, Lei; Okubo, Hiroaki; Miura, Tsuyoshi; Itoh, Akichika Advanced Synthesis and Catalysis, 2010 , vol. 352, # 14-15 p. 2383 - 2386

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Citation Number: 15

Abstract

Organic gem-dihydroperoxides and their derived peroxides have attracted a great deal of attention as potential antimalarial active compounds against the background the increasing resistance of malaria parasites to alkaloid medicine, since artemisinin with an endoperoxide bridge structure shows effective antimalarial activity against multidrug-resistant malaria.1 In addition, from the view point of organic synthesis, gem-dihydroperoxides have been also known to play an ...