Catalytic method for the reduction of lactones to lactols

X Verdaguer, SC Berk…

Index: Verdaguer, Xavier; Berk, Scott C.; Buchwald, Stephen L. Journal of the American Chemical Society, 1995 , vol. 117, # 50 p. 12641 - 12642

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Citation Number: 53

Abstract

The development of selective catalysts for use in organic synthesis is of great current interest.'S2 Additional challenges to the chemist include the development of processes which employ easily manipulated reagents, and which can be carried out at ambient temperature without the need for rigorously anhydrous andor anaerobic conditions. For a long time diisobutylaluminum hydride (DIBALH) has been the reagent of choice for the reduction of lactones to lactol~.~ ...

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