Microwave??Assisted One??Step Synthesis of Substituted 2??Chloromethyl??1, 3, 4??oxadiazoles

R Natero, DO Koltun, JA Zablocki

Index: Natero, Reina; Koltun, Dmitry O.; Zablocki, Jeffery A. Synthetic Communications, 2004 , vol. 34, # 14 p. 2523 - 2529

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Citation Number: 8

Abstract

We have developed a simple one??step synthesis of 2??chloromethyl??1,3,4??oxadiazoles from commercially available acylhydrazides using 1??chloro??2,2,2??trimethoxyethane as a solvent under microwave irradiation. ... We have developed a simple one??step synthesis of 2??chloromethyl??1,3,4??oxadiazoles from commercially available acylhydrazides using 1??chloro??2,2,2??trimethoxyethane as a solvent under microwave irradiation.