Tetrahedron Letters

Copper-catalyzed methyl esterification of aromatic aldehydes and benzoic alcohols by TBHP as both oxidant and methyl source

P Li, J Zhao, R Lang, C Xia, F Li

Index: Li, Pan; Zhao, Jingjing; Lang, Rui; Xia, Chungu; Li, Fuwei Tetrahedron Letters, 2014 , vol. 55, # 2 p. 390 - 393

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Citation Number: 19

Abstract

Abstract A copper-catalyzed synthesis of methyl esters from aromatic aldehydes in the presence of tert-butyl hydrogen peroxide (TBHP) was developed via a radical reaction mechanism. TBHP acts not only as an efficient oxidant, but also as a green methyl source in such transformation. Moreover, this method could also be efficiently extended to the methyl esterification of benzylic alcohols.

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