An efficient and recyclable silica??supported carbene–Cu (II) catalyst for the oxidative coupling reaction of terminal alkynes with H??phosphonates under base??free …

P Liu, J Yang, P Li, L Wang

Index: Liu, Ping; Yang, Jin; Li, Pinhua; Wang, Lei Applied Organometallic Chemistry, 2011 , vol. 25, # 11 p. 830 - 835

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Citation Number: 23

Abstract

Alkynylphosphonates, as important topical phosphorus element scaffolds for the construction of structurally sophisticated phosphorus compounds, are broadly found in bioactive natural products and therapeutic molecules.[1] Therefore, considerable effort has been made to develop efficient strategies for preparing them. In general, reaction of (RO) 2P (O) Cl with Li or Mg acetylene is one of the most common and efficient methods for the ...