Total synthesis of the potent mutagen S-3-(dodeca-1, 3, 5, 7, 9-pentaenyloxy) propane-1, 2-diol

KC Nicolaou, R Zipkin, D Tanner

Index: Nicolaou, K. C.; Zipkin, Robert; Tanner, David Journal of the Chemical Society, Chemical Communications, 1984 , # 6 p. 349 - 350

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Citation Number: 16

Abstract

Total Synthesis of the Potent Mutagen (S)-3-(Dodeca-l,3,5,7,9-pentaenyloxy)propane- 1,2-diol ... K. C. Nicolaou,* Robert Zipkin, and David Tanner Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA ... A total synthesis of the mutagenic (S)-3-(dodeca-l,3,5,7,9-pentaenyloxy)propane-l,2-diol (1) from (R)-glycerol acetonide (Z), potassium glutaconate (6), and the diphenylphosphine oxide (1 1) is reported.

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