Copper (I)-catalyzed asymmetric alkene aziridination mediated by PhI (OAc) 2: a facile one-pot procedure
HL Kwong, D Liu, KY Chan, CS Lee, KH Huang…
Index: Kwong, Hoi-Lun; Liu, Di; Chan, Ka-Yee; Lee, Chi-Sing; Huang, Ka-Hung; Che, Chi-Ming Tetrahedron Letters, 2004 , vol. 45, # 20 p. 3965 - 3968
Full Text: HTML
Citation Number: 56
Abstract
A facile one-pot procedure for copper-catalyzed PhI (OAc) 2-mediated asymmetric alkene aziridination had been developed. Commercially available PhI (OAc) 2 and sulfonamides were used to generate the nitrene precursors (PhI NR) in situ for olefin aziridination. This one-pot procedure had been optimized using 4-nitrobenzenesulfonamide as the nitrene source. With 5mol% of the chiral copper catalyst, these conditions afforded 94% yield of ...
Related Articles:
β 3-Amino acids by nucleophilic ring-opening of N-nosyl aziridines
[Farras, Jaume; Ginesta, Xavier; Sutton, Peter W; Taltavull, Joan; Egeler, Frank; Romea, Pedro; Urpi, Felix; Vilarrasa, Jaume Tetrahedron, 2001 , vol. 57, # 36 p. 7665 - 7674]
[Taylor, Sophia; Gullick, John; McMorn, Paul; Bethell, Donald; Page, Philip C. Bulman; Hancock, Frederick E.; King, Frank; Hutchings, Graham J. Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 9 p. 1714 - 1723]
[Jeffs, Laura; Arquier, Damien; Kariuki, Benson; Bethell, Donald; Page, Philip C. Bulman; Hutchings, Graham J. Organic and Biomolecular Chemistry, 2011 , vol. 9, # 4 p. 1079 - 1084]
[Taylor, Sophia; Gullick, John; McMorn, Paul; Bethell, Donald; Page, Philip C. Bulman; Hancock, Frederick E.; King, Frank; Hutchings, Graham J. Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 9 p. 1714 - 1723]