Regio-and enantioselective iridium-catalyzed allylation of thiophenol: synthesis of enantiopure allyl phenyl sulfides
S Zheng, N Gao, W Liu, D Liu, X Zhao, T Cohen
Index: Zheng, Shengcai; Gao, Ning; Liu, Wei; Liu, Dongge; Zhao, Xiaoming; Cohen, Theodore Organic Letters, 2010 , vol. 12, # 20 p. 4454 - 4457
Full Text: HTML
Citation Number: 28
Abstract
Herein, we report the formation of chiral allylic phenyl sulfides via iridium-catalyzed enantioselective allylations of sodium thiophenoxide 3. This represents the first example of the use of transition-metal-catalyzed enantioselective allylations of thiophenol to form allyl phenyl sulfides in good yields and with excellent enantioselectivities. Important potential uses of such products are discussed below. ... We first aimed at optimizing reaction conditions for the ...
Related Articles:
Fast Ruthenium??Catalysed Allylation of Thiols by Using Allyl Alcohols as Substrates
[Zaitsev, Alexey B.; Caldwell, Helen F.; Pregosin, Paul S.; Veiros, Luis F. Chemistry - A European Journal, 2009 , vol. 15, # 26 p. 6468 - 6477]
Fast Ruthenium??Catalysed Allylation of Thiols by Using Allyl Alcohols as Substrates
[Zaitsev, Alexey B.; Caldwell, Helen F.; Pregosin, Paul S.; Veiros, Luis F. Chemistry - A European Journal, 2009 , vol. 15, # 26 p. 6468 - 6477]
[Nishiyama, Hisao; Itagaki, Kazuyoshi; Sakuta, Koji; Itoh, Kenji Tetrahedron Letters, 1981 , vol. 22, # 52 p. 5285 - 5288]