Organic Process Research & Development

Studies in Selectivity Aspects in the Synthesis of Aliphatic α-Bromoaldehydes

S Mukhopadhyay

Index: Mukhopadhyay, Sudip Organic Process Research and Development, 1999 , vol. 3, # 6 p. 480 - 484

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Abstract

A highly selective process scheme was developed to synthesize α-bromoaldehydes by regulating the important process parameters from a reaction-engineering point of view. Thus, α-bromobutyraldehyde and α-bromoheptaldehyde were synthesized in very high selectivity starting with butyraldehyde and heptaldehyde. In the bromination reaction at 40% conversion ratio, the selectivity was as high as 98% by using liquid bromine as the ...