β-Hydroxyalkylation of sterically hindered phenols with epoxides in acid medium

…, SA Amitina, TG Egorova, VG Vasiliev

Index: Krysin; Amitina; Egorova; Vasiliev Russian Journal of General Chemistry, 2011 , vol. 81, # 2 p. 354 - 360

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Abstract

Abstract Reactions of 2, 6-dialkylphenols with ethylene oxide, propylene oxide and epichlorohydrin in the presence of SnCl 4 at the temperature from− 5 to+ 5° C leads to the formation of respective phenols containing a hydroxy group in the β-position of the aliphatic chain of the para-substituent. The conditions for maximum selectivity of the reaction of 2, 6-di- tert-butylphenol with ethylene oxide were determined. By HPLC-MS method the directions ...