Cyclic guanidines. 17. Novel (N-substituted amino) imidazo [2, 1-b] quinazolin-2-ones: water-soluble platelet aggregation inhibitors

F Ishikawa, J Saegusa, K Inamura…

Index: Ishikawa; Saegusa; Inamura; Sakuma; Ashida Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1387 - 1393

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Citation Number: 29

Abstract

A series of novel 1, 2, 3, 5-tetrahydroimidazo [2, 1-b] quinazolin-2-one derivatives substituted with a secondary amino group has been prepared and tested for the activities of inhibiting platelet aggregation in rats in vitro and ex vivo. Most of the compounds were ...