Lipidic Peptides, XIV. Conversion of Racemic Lipidic Amino Acids into Sphingosine and Ceramide Analogues and 1, 2??Diamines
G Kokotos, V Constantinou??Kokotou…
Index: Kokotos, George; Constantinou-Kokotou, Violetta; Fernandez, Esther del Olmo; Toth, Istvan; Gibbons, William A. Liebigs Annalen der Chemie, 1992 , # 9 p. 961 - 964
Full Text: HTML
Citation Number: 10
Abstract
Abstract N-Protected racemic lipidic amino acids 1a–h were converted directly into ceramide analogues 2a–h by chemoselective reduction of their corresponding mixed anhydrides with sodium tetrahydroborate. Conversion of the compounds 1a, b into the corresponding acyl azides, followed by catalytic hydrogenation gave the N-monoprotected lipidic 1, 2-diamines 5a, b. The sphingosine analogues 7a–c and the free 1, 2-diamines 6a, b were synthesized ...
Related Articles:
Synthesis and evaluation of some lipidic aminoalcohols and diamines as immunomodulators
[Olmo, Esther del; Plaza, Alvaro; Muro, Antonio; Martinez-Fernandez, Antonio R.; Nogal-Ruiz, Juan J.; Lopez-Perez, Jose L.; Feliciano, Arturo San Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6091 - 6095]
Synthesis and evaluation of some lipidic aminoalcohols and diamines as immunomodulators
[Olmo, Esther del; Plaza, Alvaro; Muro, Antonio; Martinez-Fernandez, Antonio R.; Nogal-Ruiz, Juan J.; Lopez-Perez, Jose L.; Feliciano, Arturo San Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6091 - 6095]
Synthesis and evaluation of some lipidic aminoalcohols and diamines as immunomodulators
[Olmo, Esther del; Plaza, Alvaro; Muro, Antonio; Martinez-Fernandez, Antonio R.; Nogal-Ruiz, Juan J.; Lopez-Perez, Jose L.; Feliciano, Arturo San Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6091 - 6095]
Synthesis and evaluation of some lipidic aminoalcohols and diamines as immunomodulators
[Olmo, Esther del; Plaza, Alvaro; Muro, Antonio; Martinez-Fernandez, Antonio R.; Nogal-Ruiz, Juan J.; Lopez-Perez, Jose L.; Feliciano, Arturo San Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6091 - 6095]
Synthesis and evaluation of some lipidic aminoalcohols and diamines as immunomodulators
[Olmo, Esther del; Plaza, Alvaro; Muro, Antonio; Martinez-Fernandez, Antonio R.; Nogal-Ruiz, Juan J.; Lopez-Perez, Jose L.; Feliciano, Arturo San Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6091 - 6095]