Tetrahedron letters

A short and efficient synthesis of echiguanines A and B: Potent inhibitors of phosphatidylinositol-4-kinase

C Shih, Y Hu

Index: Shih, Chuan; Hu, Ying Tetrahedron Letters, 1994 , vol. 35, # 27 p. 4677 - 4680

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Citation Number: 10

Abstract

Abstract An efficient synthesis which utilizes a palladium catalyzed carbonylation reaction between 2-pivaloyl-7-iodo-7-deazaguanine and 3-aminopropionitrile as a key step was developed for the preparation of a new class of pyrrolopyrimidine based PI4-Kinase