Tetrahedron letters

Selective and efficient oxidation of sulfides to sulfoxides with N-bromosuccinimide in the presence of β-cyclodextrin in water

K Surendra, NS Krishnaveni, VP Kumar, R Sridhar…

Index: Surendra; Krishnaveni, N. Srilakshmi; Kumar, V. Pavan; Sridhar; Rao, K. Rama Tetrahedron Letters, 2005 , vol. 46, # 27 p. 4581 - 4583

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Citation Number: 84

Abstract

A simple and highly selective oxidation of sulfides to sulfoxides with N-bromosuccinimide (NBS) catalyzed by β-cyclodextrin in water has been developed. A series of sulfides were oxidized selectively at room temperature in excellent yields. This reaction proceeds without over-oxidation to sulfones under mild conditions using water as a solvent and has many advantages over the existing methodologies.