Synthesis of Dienes by Palladium??Catalyzed Couplings of Tosylhydrazones with Aryl and Alkenyl Halides

…, M Tomas??Gamasa, F Aznar, C Valdes

Index: Barluenga, Jose; Tomas-Gamasa, Maria; Aznar, Fernando; Valdes, Carlos Advanced Synthesis and Catalysis, 2010 , vol. 352, # 18 p. 3235 - 3240

Full Text: HTML

Citation Number: 39

Abstract

Abstract Two different combinations of coupling partners can be employed for the synthesis of conjugated dienes by palladium-catalyzed cross-coupling with tosylhydrazones: α, β- unsaturated ketone and aryl halide or alkenyl halide and non-conjugated tosylhydrazone. Depending on the substrate, a vinylogous hydride elimination is responsible for the formation of the final dienes.