Ionophore antibiotic X-14547A. Degradation studies and stereoselective construction of the" right wing"(C11-C25 fragment) by an intramolecular Diels-Alder reaction

KC Nicolaou, RL Magolda

Index: Nicolaou, Kyriacos C.; Magolda, Ronald L. Journal of Organic Chemistry, 1981 , vol. 46, # 7 p. 1506 - 1508

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Citation Number: 34

Abstract

Summary: Studies directed toward the total synthesis of the ionophore antibiotic X-14547A are reported. Degradation methods led to a number of “left-wing” fragments, whereas synthetic operations led to a “right-wing''fragment, in a highly efficient and stereoselective manner via an intramolecular Diels-Alder reaction.