Synthesis of novel bioactive pyrazolothiazoles

S Yuvaraj, M Mendon, A Almeida, M Dhiman…

Index: Yuvaraj; Mendon, Monica; Almeida, Asha; Dhiman, Mini; Girish, Manju Medicinal Chemistry Research, 2014 , vol. 23, # 5 p. 2667 - 2675

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Citation Number: 2

Abstract

Abstract The synthesis of 3-{substituted 1, 3-thiazol-5-yl}-1-substituted 1 H-pyrazole-4- carboxylates (4a–n) has been achieved in facile manner by the reaction between 2- aminothiazoles, dimethylformamide dimethyl acetal and hydrazine. All the synthesized compounds were characterized by spectral and elemental analyses. These compounds were also evaluated against anti-inflammatory activity and showing promising activities.