Tetrahedron

Synthesis of mono-and sesquiterpenoids—IV: Racemic sabina ketone

K Mori, M Ohki, M Matsui

Index: Mori,K. et al. Tetrahedron, 1970 , vol. 26, p. 2821 - 2824

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Citation Number: 14

Abstract

RECENTLY a total synthesis of racemic sabinene (II) and cis- and zruns-sabinene hydrates (II&b) via sabina ketone (I) has been accomplished employing the Simmons-Smith reaction for the construction of the bicycle 13.1-01 hexane ring systerul~ 2 Herein is described an alternate synthesis of racemic sabina ketone (I) by the intramolecular a-ketocarbene-olelin addition.3 The key intermediate XII was prepared as follows. Ethyl isopropylcyanoacetate (IV)' was ...