The chemistry of 1, 2, 5??thiadiazoles V. Synthesis of 3, 4??diamino??1, 2, 5??thiadiazole and [1, 2, 5] thiadiazolo [3, 4??b] pyrazines

AP Komin, M Carmack

Index: Komin,A.P.; Carmack,M. Journal of Heterocyclic Chemistry, 1976 , vol. 13, p. 13 - 22

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Citation Number: 37

Abstract

Abstract The o-diamine, 3, 4-diamino-1, 2, 5-thiadiazole (2), was synthesized from 3, 4- dichloro-1, 2, 5-thiadiazole (3) hy three methods. Aqueous glyoxal cyclized 2 into [1, 2, 5] thiadiazolo [3, 4–6]-pyrazine (14). 3, 4-Dichloro-1, 2, 5-thiadiazole 1, 1-dioxide (18) reaeted with 2 to give 1, 3-dihydro-bis [1, 2, 5] thiadiazolo [3, 4-b: 3′, 4′-e] pyrazine 2, 2-dioxide (19). The reaction of 2 with selenium oxyehloride led to [1, 2, 5] selenadiazolo [3, 4-c][1, 2, ...