Tetrahedron Letters

Oxidation of alcohols by transition metal complexes part V. Selective catalytic monoalkylation of arylacetonitriles by alcohols

R Grigg, TRB Mitchell, S Sutthivaiyakit, N Tongpenyai

Index: Grigg, Ronald; Mitchell, Thomas R. B.; Sutthivaiyakit, Somyote; Tongpenyai, Ngampong Tetrahedron Letters, 1981 , vol. 22, # 41 p. 4107 - 4110

Full Text: HTML

Citation Number: 78

Abstract

Abstract Selective catalytic monoalkylation of arylacetonitriles by primary alcohols can be achieved at≤ 100 using a catalyst prepared in situ from rhodium trichloride, triphenylphosphine and sodium carbonate. RuH 2 (PPh 3) 4 is a more effective catalyst for this process.